Disagree that it's readable. The parens are great - they show exactly where a function call starts and where it ends. The program is a tree!

+1 That thing is gross. I'd edit so much more slowly if I had to go back to a messy, complex syntax. At least without a very clever / specialized editor effectively undoing the change for me.

Infix is occasionally more readable for math, but I'd rather have a macro to transform a delimited section of infix code than to mess with the language.

Infix is only easy to read if you're only used to it. Not inherently better - I'd say opposite even.

Also, I don't want to live without Paredit (or Smartparens)

To my mind, parinfer provides the benefits of significant whitespace in Lisp without any of the disadvantages.